What Is Radiesse?

Radiesse is a regenerative biostimulator dermal filler that provides both immediate volumization and long-term skin regeneration. Its key component, Calcium Hydroxylapatite (CaHA), is a substance naturally found in the human body.

This dual-action mechanism allows Radiesse to:

• • Deliver immediate correction of deep folds and volume loss

• • Stimulate natural collagen and elastin production over time

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How Many Types of Radiesse Are There? What’s the Difference?

Currently, Radiesse is available in two main formulations: Radiesse Classic and Radiesse Plus. Each is designed for different treatment goals.

TypeBest ForKey BenefitRadiesse ClassicSkin rejuvenation / Large treatment areasExcellent collagen stimulation and smooth distributionRadiesse PlusLifting / Facial contouringHigher lifting capacity and structural support

Radiesse Classic

The original formulation primarily focused on improving overall skin quality.

Composition

• • Calcium Hydroxylapatite (CaHA)

• • CMC Gel

• • No lidocaine premixed

How It’s Used
Physicians typically dilute it with lidocaine and saline prior to injection to allow smoother spread and better distribution in superficial to mid dermal layers.

Ideal For

• • Full face skin rejuvenation

• • Neck

• • Hands

• • Patients seeking firmer, more elastic, and revitalized skin

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Radiesse Plus

An advanced formulation designed for enhanced lifting and facial contouring.

Composition

• • Calcium Hydroxylapatite (CaHA)

• • CMC Gel

• • Pre-mixed with 0.3% Lidocaine

How It’s Used
Ready to inject without additional mixing. Its higher viscosity and elasticity provide stronger structural support and better projection.

Ideal For

• • Jawline definition

• • Chin augmentation

• • Cheek contouring

• • Facial reshaping requiring stronger lifting power

Key Benefits

✔ Dual-Effect Treatment

Instant volumizing results combined with long-term collagen stimulation.

✔ Scaffold Effect

CaHA microspheres act as a structural framework, encouraging new collagen formation around the particles, leading to firmer and more resilient skin.

✔ Long-Lasting Results

Results typically last 12–18 months, and in some patients up to 24 months, depending on individual factors.

✔ Safety Standards

Radiesse is approved by the U.S. Food and Drug Administration and is also registered with the Thai Food and Drug Administration.