Pluryal HPN Technology

What is Pluryal?

Pluryal is a European aesthetic brand specializing in advanced injectable solutions, including Hyaluronic Acid (HA) fillers and Polynucleotide-based skin regeneration products.

One of the brand’s key innovations is HPN Technology (Highly Pure Polynucleotides) — a high-purity Polynucleotide technology designed to enhance skin repair and regeneration. Through advanced purification processes, proteins and impurities are removed to ensure safety, biocompatibility, and optimal clinical performance.

Polynucleotides (PN) support cellular repair mechanisms, stimulate collagen production, and improve skin elasticity, helping restore healthier and stronger skin from within.

Among the most popular products are Pluryal Silk, Pluryal Densify, and Pluryal Biosculpture, each formulated for specific aesthetic indications.

1) Pluryal Silk

Key Ingredient:

• Low-density Hyaluronic Acid (HA)

Indications:

• • Fine lines and superficial wrinkles

• • Delicate areas such as under-eye and perioral regions

• • Skin hydration and surface refinement

Highlights:

• • Smooth, lightweight texture

• • Excellent spreadability in superficial dermal layers

• • Natural-looking results for detailed correction

Summary: Ideal for subtle refinement and fine-line correction with enhanced hydration.

2) Pluryal Densify

Key Ingredient:

• Medium-density Hyaluronic Acid (HA)

• Molecular structure optimized to enhance dermal firmness

Indications:

• • Skin laxity

• • Reduced elasticity

• • Dull or dehydrated skin

Highlights:

• • Improves dermal density

• • Supports collagen stimulation

• • Enhances skin elasticity and resilience

Summary: Designed for skin quality improvement and structural support rather than simple volume replacement.

3) Pluryal Biosculpture

Key Ingredient:

• High-density Hyaluronic Acid (HA)

• Formulated for deep structural support and volumization

Indications:

• • Deep folds (e.g., nasolabial folds)

• • Facial contouring (chin, cheeks, temples)

• • Structural volume restoration

Highlights:

• • High cohesivity and shape retention

• • Suitable for deep dermal and subdermal injection

• • Provides defined yet natural-looking contour enhancement

Summary: Ideal for deep volumization and facial contouring with long-lasting structural support.