Chinese Researchers Reveal FMD Enhances Tumor Immunity

Beijing, (Xinhua) — Recently, a research team from Zhongshan Hospital affiliated with Fudan University in Shanghai, eastern China, unveiled a new mechanism by which a Fasting-Mimicking Diet (FMD) helps enhance tumor immunity.

A fasting-mimicking diet involves short-term consumption of low-calorie foods designed to mimic the effects of fasting while still allowing limited food intake. This method aims to stimulate metabolic changes, promote cell repair, reduce inflammation, and may offer various benefits such as improved metabolic health and increased lifespan without the need for complete fasting.

A research article published in the journal Gut stated that the research team found that a fasting-mimicking diet could increase the number of B. pseudolongum bacteria, which stimulate the production of CD8+ T memory cells, thereby inhibiting colorectal cancer.

This study not only confirms that a fasting-mimicking diet has an anti-tumor effect through significant modulation of gut microbiota but also reveals a new mechanism by which microbial metabolism regulates immune cell function.

This new discovery provides a theoretical foundation for the application of fasting-mimicking diets in the treatment of colorectal cancer and offers insights into nutritional care before and after surgery for colorectal cancer patients.

Meanwhile, the incidence and mortality rates of colorectal cancer, a highly prevalent malignant tumor worldwide, continue to rise in China. The number of patients in the country accounts for one-third of the global total, with inappropriate dietary habits being a major risk factor.

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Xinhuathai News