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At SAFE Fertility Group, we provide Intrauterine Insemination (IUI) as one of the fertility treatment options for individuals and couples who are experiencing difficulty conceiving naturally. IUI is a simple, safe, and commonly used assisted reproductive procedure that helps increase the chance of pregnancy by placing specially prepared sperm directly into the uterus around the time of ovulation.
This procedure is designed to bring healthy, fast-moving sperm closer to the egg, increasing the opportunity for fertilization to occur naturally inside the body.
Intrauterine Insemination, or IUI, is a fertility procedure in which prepared sperm is placed directly into the uterus during the most fertile period of a woman’s menstrual cycle.
Before the procedure, the semen sample is processed in the laboratory to separate healthy, fast-moving sperm from non-motile sperm and other substances in the semen. This preparation process is often called sperm washing.
The selected sperm is then inserted into the uterus using a very thin tube. By placing sperm closer to the fallopian tubes around the time of ovulation, IUI can help improve the chance that sperm will meet the egg and fertilization may occur naturally.
IUI may be recommended for individuals or couples with certain fertility challenges, especially when the condition is mild or unexplained. It may be suitable for:
Couples with unexplained infertility
Women with ovulation problems
Couples with mild male factor infertility
Men with slightly low sperm count or reduced sperm motility
Couples who have difficulty with timed intercourse
Women using fertility medication to support ovulation
Couples seeking a less invasive fertility treatment before considering IVF or ICSI
A consultation with a fertility specialist is important to determine whether IUI is the most appropriate treatment option based on age, medical history, ovarian function, sperm quality, and overall fertility condition.
The doctor will review the couple’s medical history and may recommend fertility investigations, including ultrasound examination, hormone testing, ovulation assessment, and semen analysis.
The female patient may be advised to take fertility medication to stimulate ovulation, usually within day 1 to day 5 of the menstrual cycle, depending on the treatment plan.
The doctor will monitor follicle development closely through ultrasound scans and blood tests to determine the best timing for insemination.
On the day of the procedure, the male partner provides a semen sample. It is generally recommended to avoid ejaculation for approximately 2–5 days before sperm collection to help ensure an appropriate sample.
The semen sample is taken to the laboratory for sperm washing. This process separates healthy, fast-moving sperm from non-motile sperm and removes substances that may affect sperm function or cause irritation in the uterus.
During the procedure, the patient lies on an examination table. The doctor gently places a speculum into the vagina to visualize the cervix, similar to a Pap smear examination.
The prepared sperm is then passed through the cervix and placed directly into the uterus using a long, very thin catheter.
The procedure usually takes only a few minutes and is generally painless.
After insemination, the patient may remain lying down for approximately 30 minutes. Most patients can return to normal daily activities shortly after the procedure.
Approximately two weeks after IUI, the patient will take a pregnancy test to check whether the procedure was successful.
The success rate of IUI depends on several important factors, including the woman’s age, egg quality, sperm quality, ovulation response, and the condition of the uterine lining on the day of insemination.
General estimated IUI success rates may vary by age group:

As women age, the chance of conception may decrease due to changes in egg quality. For this reason, IUI may not be the preferred treatment option for women over 40, and other fertility treatments such as IVF or ICSI may be considered.
The success of IUI can be influenced by several factors, including:
Age of the female partner
Number and quality of available eggs
Ovulation timing
Sperm concentration and motility after preparation
Thickness and quality of the endometrium, or uterine lining
Underlying fertility conditions
Number of previous fertility treatment attempts
At SAFE Fertility Group, the doctor will carefully monitor these factors to plan the most suitable timing and treatment approach for each patient.
The doctor may prescribe fertility medication to help stimulate ovulation, usually starting between day 1 and day 5 of the menstrual period.
During the treatment cycle, the doctor will monitor the patient closely with ultrasound examinations and blood tests. This helps determine when the egg is ready and when the IUI procedure should be scheduled.
The goal is to perform insemination at the most appropriate time around ovulation to maximize the chance of pregnancy.
The male partner will provide a semen sample on the day of the IUI procedure.
To prepare for sperm collection, it is generally recommended to avoid ejaculation for approximately 2–5 days before the procedure.
After collection, the semen sample will be immediately sent to the laboratory for sperm washing. This process helps select healthy, motile sperm and remove unnecessary substances from the semen before insemination.
SAFE Fertility Group provides IUI treatment with a patient-centered approach, supported by experienced fertility specialists, laboratory professionals, and advanced reproductive care standards.
Our doctors evaluate each patient carefully and recommend the most suitable fertility treatment based on medical condition, age, ovarian function, and sperm quality.
Regular ultrasound scans and blood tests help identify the best timing for insemination, which is an important factor for IUI success.
Semen samples are prepared by trained laboratory professionals to select healthy, fast-moving sperm for the insemination procedure.
IUI is a minimally invasive procedure that usually takes only a few minutes, is generally painless, and allows patients to return to normal daily activities afterward.
Each IUI cycle is planned based on the individual needs of the patient or couple, with clear communication and support throughout the process.
IUI is a widely used fertility treatment that may be suitable for couples seeking a safe, affordable, and less invasive option to improve their chance of pregnancy.
At SAFE Fertility Group, our specialists are ready to provide professional consultation, careful monitoring, and personalized fertility care to support you throughout your journey.
Contact SAFE Fertility Group today to schedule a personal consultation and learn whether IUI is the right fertility treatment option for you.
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SAFE Fertility Group
Bangkok, Thailand

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